Helpful Lexicon: BRACHYTHERAPY: HDR: High Dose Radiotherapy (temporary) AND (permanent) aka SEEDs, aka interstitial radiotherapy ('IRT' 'MayoSpeak'). 'RADIATION': External Beam Radiotherapy (EBRT). The latter includes SBRT, [stereotactic beam radio therapy] < 5 sessions of a higher dose, ideal candidate
are in the intermediate group favorable and unfavorable G7 {3/4, 4/3}. IMRT, (Intensity Modulated Radiation Therapy) is another computer generated earlier technology of lower dose over 20-40 sessions. Recent research suggests moderated (fewer) IMRT sessions are equi-effective as the traditional greater number. Apparently unlike other bodily tissues the Prostate is more sensitive to all forms of radiation. Adding neoadjuvant ADT (androgen deprivation therapy) increases that sensitivity by 67%, (There is some thought that adding Nubeqa brings the sensitivity to 100% of the baseline?) SYSTEMIC (Intravenous) 'radiotherapy' The most common prostate cancer can be targeted by the immune system loaded with a radioactive isotope (ligand). The first of several in the pipeline is PLUVICTO (PSMA Lutetium 177). (It is a 'first cousin of the substance in a PSMA PET-CT scan) Some well off individuals are resorting to medical tourism, going to Germany, India etc. to get the infusions of PLUVICTO. Currently it is not being used for cancer solely found in the prostate. I suspect ultimately systemic ligand radiotherapy will be available for non metastatic disease.