Feedback on Linzess for Irritable Bowel-C or Chronic Constipation

Posted by sue225 @sue225, Mar 9, 2019

I have both of the above-conditions. Took Linzess, (called Constella in Canada) and got terrible stomach pain. Feeling desperate and thinking about trying it one more time. Interested in hearing what kind of experiences other people have had with linaclotide/linzess.

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I tried it!! Didn't work!! Neither did Linzess or Amtisia (sp?) Trulance and MiraLAX work for me...prayers for you!!

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Profile picture for standinginfaith @standinginfaith

I tried it!! Didn't work!! Neither did Linzess or Amtisia (sp?) Trulance and MiraLAX work for me...prayers for you!!

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Me either, I’m up to 30 laxatives at bedtime. Running out of time.

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Profile picture for Joanne Narna @mothermary1

Me either, I’m up to 30 laxatives at bedtime. Running out of time.

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Oh my goodness!! Have you tried the Trulance?? And I also Miralax every PM at dinner with a full glass of water..some days it might take 2 doses of Miralax.. somedays I can go without..and I do try to drink 3 bottles of water a day..and eat one Thomas Multigrain English Muffin (the wheat one has sucralose..a gut bacteria no-no) with Country Crock plant butter every night..(8 gr fiber) and 2 Vanilla Plant based Ensures a day (5 gr fiber each) and a VSL3 Probiotic..daily.. good probiotic..Amazon has them.. have to be refrigerated.. they ship them really well with I think it's dry ice..pricey.. but really worth it.. I pray some of this helps you!!

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Profile picture for standinginfaith @standinginfaith

Oh my goodness!! Have you tried the Trulance?? And I also Miralax every PM at dinner with a full glass of water..some days it might take 2 doses of Miralax.. somedays I can go without..and I do try to drink 3 bottles of water a day..and eat one Thomas Multigrain English Muffin (the wheat one has sucralose..a gut bacteria no-no) with Country Crock plant butter every night..(8 gr fiber) and 2 Vanilla Plant based Ensures a day (5 gr fiber each) and a VSL3 Probiotic..daily.. good probiotic..Amazon has them.. have to be refrigerated.. they ship them really well with I think it's dry ice..pricey.. but really worth it.. I pray some of this helps you!!

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Unfortunately this is a five year ordeal for me and nothing works. I was drinking too much water and was diagnosed with hyponatremia, who would have thought.
Now Gastro cut me to 32 ounces per day, at most. Fiber binds me even more. My diet is extremely limited. No dairy, no gluten and no sugar. I get about a quarter cup of mashed fresh carrots a day and that is about all I can handle for fiber. Carbs are another issue. I blend a lot.
Thanks for the advice but I’ve tried everything. Beware of MiraLAX because for whatever reason it’s what most doctors prescribe. I don’t get why.
It has PEG and the safety of it daily. They say it’s fine short term but no studies done long term. It concerns me.

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Profile picture for Joanne Narna @mothermary1

Unfortunately this is a five year ordeal for me and nothing works. I was drinking too much water and was diagnosed with hyponatremia, who would have thought.
Now Gastro cut me to 32 ounces per day, at most. Fiber binds me even more. My diet is extremely limited. No dairy, no gluten and no sugar. I get about a quarter cup of mashed fresh carrots a day and that is about all I can handle for fiber. Carbs are another issue. I blend a lot.
Thanks for the advice but I’ve tried everything. Beware of MiraLAX because for whatever reason it’s what most doctors prescribe. I don’t get why.
It has PEG and the safety of it daily. They say it’s fine short term but no studies done long term. It concerns me.

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Bless your heart!! I am so sorry!! I am concerned about the MiraLax myself as it is also used in anitfreeze.. IDK.. all we can do is pray!

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Profile picture for standinginfaith @standinginfaith

Oh my goodness!! Have you tried the Trulance?? And I also Miralax every PM at dinner with a full glass of water..some days it might take 2 doses of Miralax.. somedays I can go without..and I do try to drink 3 bottles of water a day..and eat one Thomas Multigrain English Muffin (the wheat one has sucralose..a gut bacteria no-no) with Country Crock plant butter every night..(8 gr fiber) and 2 Vanilla Plant based Ensures a day (5 gr fiber each) and a VSL3 Probiotic..daily.. good probiotic..Amazon has them.. have to be refrigerated.. they ship them really well with I think it's dry ice..pricey.. but really worth it.. I pray some of this helps you!!

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I see you have said that Sucralose is a gut bacteria no-no. I take Metamucil, 1 T in 8-10 oz of water twice daily. It has Sucrose in it. Is this the same thing?

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Profile picture for busylady @busylady

I see you have said that Sucralose is a gut bacteria no-no. I take Metamucil, 1 T in 8-10 oz of water twice daily. It has Sucrose in it. Is this the same thing?

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Google says that Sucralose is and artificial sweetener.. and sucrose is a natural one.. I hope this helps you some!! Great "investigation" on your part!! They hide so much in the things we consume!! Prayers for you!!

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Profile picture for standinginfaith @standinginfaith

Google says that Sucralose is and artificial sweetener.. and sucrose is a natural one.. I hope this helps you some!! Great "investigation" on your part!! They hide so much in the things we consume!! Prayers for you!!

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Standing in faith (love that!) How kind of you! And prayers for you as well.

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Profile picture for busylady @busylady

I see you have said that Sucralose is a gut bacteria no-no. I take Metamucil, 1 T in 8-10 oz of water twice daily. It has Sucrose in it. Is this the same thing?

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No, it is not, but also you don’t want anything with that in it, unless you find out what it is. I read everything. Google what are sugars. They are disguised under many names. You need to probably stay away from all those. I also eat anti inflammatory foods. My diet is the same day in and out but I’ve never been a foodie, so I adjusted easily. I also keep a diary too.

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Profile picture for standinginfaith @standinginfaith

Google says that Sucralose is and artificial sweetener.. and sucrose is a natural one.. I hope this helps you some!! Great "investigation" on your part!! They hide so much in the things we consume!! Prayers for you!!

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I have had severe chronic constipation, IBS-C for a long time too, I so understand the struggle and frustration. All the fiber supplements made things worse and I cannot tolerate a lot of water because of intersticial cystitis and some incontinence. My G.I. doctor finally gave me samples of Linzess a week ago and that did not work. I ended up un E.D. on Monday after trying enema to help discomfort and all the straining caused a rectal prolapse. I am now trying the Miralax again twice a day, Senna 8.6 mg twice a day and lactulose twice a day. Now I am afraid that I have another proplapse with bowel movement, I have appointment with colorectal surgeon in August.

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