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I’ve been on Amiodarone since middle of October 2024. Loaded in, then dropped to 200 mg, then in February to 100 mg. Having a PFA Ablasion at Mayo Clinic in August. I have only had two afib attacks. The second was very bad. Honestly except for tying me up (but colace helps that) the amiodarone has been wonderful. So far so good. Yes, there is the fatigue and shortness of breath, but it has kept me in sinus rhythm. Doctor says I will need to stay on it three months after the procedure.

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Replies to "I’ve been on Amiodarone since middle of October 2024. Loaded in, then dropped to 200 mg,..."

Which doctor said this? Was it a GP, a cardiologist, or an electrophysiologist?
Some patients, for reasons unknown to me, have been advised by their electrophysiologists to keep taking a minimal dose of propafenone, maybe Flecainide, possibly Sotalol or diltiazem, for a few weeks post ablation. I think it depends on the patient's history, maybe their other comorbidities that can exacerbate AF, or how cranky/irritable their heart has been lately. However, at some point an assessment of the heart's rhythm must be made to determine if the ablation has been successful, or if there are substituted arrhythmias like flutter (happens fairly often) or just a few too many PACs. Taking amiodarone for three full months may not be out of keeping with the situation, but one should be off it for about three to four weeks prior to that assesment, usually via a Holter monitor. A heart still infused with working anti-arrhythmics and beta/calcium channel blockers will be responding as much to those chemicals as they will to the albation...meaning the drugs are a 'confound'. I hope both you and your physician/expert are in agreement there, that you should be free of any confounding pharmacy for a couple or three weeks prior to the Holter.
I may be 'out to lunch' on this, as in...wrong. I would love to learn more.

I was able to stop amioderone the day of my ablation per dr ok - had no problem and no afib. Ask about it. Amioderone stays in your system for weeks after you stop.