I am prednisone free since June 2024. I alternate between extra strength Tylenol, ibuprofen, or naproxen. (Aleve). Ibuprofen and Aleve will help with both pain and inflammation control. Tylenol will simply address the pain. I find that I have a good response with the 12 hour Aleve capsule. I have also been trying to cut back on the use of the over-the-counter painkillers. The amount of pain I experience changes daily. Also barometric pressure changes seem to affect my pain levels.