greysky …I believe we are on same page, but as I have posted before I wanted off prednisone the day after I started taking it and I do believe I (being uneducated) started way to soon and by too many milligrams. I was adamant that I would live with the pain and it would go away. Wrong. After a month or two of no or little pain in initial sites of PRM and worsening in hands and wrists I drastically increased back to 14 (where I was getting relief) .. staying there for two or so weeks and then will begin to wean off only this time one milligram every 7 or 10 days to see how pain reacts. More than one doctor and multiple health sites tell us that inflammation and living with the pain is detrimental to our health both physical and mentally. So I (and each of us has to make decisions for what we believe is best for ourselves) am going to try again only slower this time.