I’m interested in your comment about taking SSRIs with a
Triptan. I had been using Ubrelvy for some time with little relief. After a recent hospitalization for the worst and intractable migraine I ever experienced, accompanied by a severe urinary tract infection, I received prescriptions for Nurtec and Imitrex when I was discharged. Those two meds aren’t taken together. I’ve used them on different days at migraine onset. I also take a monthly Ajovy injection for prevention; the effectiveness appears to be diminishing. I had the same experience with Emgality.

Nurtec doesn’t help; however, Imitrex usually relieves my headache within about a half hour. I’ve taken antidepressants for several years; perhaps that’s why Imitrex is working for me. It’s only been a few weeks since starting it, but I’m grateful for the relief with Imitrex so far. I hadn’t considered the SSRI connection.

I’ve seen postings relating to diet triggers for migraines, but haven’t connected them with anything I’ve eaten. I don’t use caffeine, cola or artificial sweeteners. Cheese and chocolate don’t bother me. My headaches seem connected to the weather, which has been awful this year. We have experienced a significant amount of rainfall, wind, followed by brief periods of pleasant weather, interspersed with chilly, cloudy days.