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Switching from Orgovyx to Bicalutamide

Prostate Cancer | Last Active: 4 hours ago | Replies (10)

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@jeffmarc

When Lupron failed me after 2 1/2 years and I became castrate resistant I went on Biclutamide in addition to Lupron. My PSA went down from .3 to .2 for three months, but then it started rising and 14 months later was at 1.2 so I went on abiraterone. In my case, I stayed on Lupron because not all of the prostate cancer has become castrate resistant just some of it, so Lupron can help still. Abiraterone Was able to keep my PSA manageable for about 2 1/2 years but caused too many heart issues.

I switched to Darolutamide And it has been working really well. I’ve been undetectable for 19 months, And after all those drugs and 15 years of treatment, that product works well.

I know a number of people who are on Darolutamide standalone And it works well, even though there is testosterone there. You might ask your doctor if it was possible to get that drug. It has the least side effects of all the lutamides. Never had problems with liver tests that I get a every month.

Staying with Orgovyx for the recommended period may give you better results. You are four months away, It may be worth hanging in there.

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Replies to "When Lupron failed me after 2 1/2 years and I became castrate resistant I went on..."

Hi Jeff, glad you’re doing well. I just started taking Abiraterone in conjunction with Orgovyx, I was curious as to what heart related side effects you experienced or was concerning enough to stop the abiraterone? Also are you exclusively on Darolutamide? Thank you.