← Return to Implications of Long Term Drug Regime

Discussion
jcaesar avatar

Implications of Long Term Drug Regime

Chronic Pain | Last Active: Jul 2, 2025 | Replies (21)

Comment receiving replies
Profile picture for jcaesar @jcaesar

Thanks so much to both of you for your responses. I wrote that one of her meds was Tylenol 3 - that's got 30mg codeine. This is Canada, so no, unless you go to a private clinic - no surgery. Of course, they do get around to you in a year or two or three even but that's hardly timely intervention. In the quest for an effective analgesic, we have already gone through Duloxtetine (the drowsiness side effect made that impossible to continue) and Gabapentin (no side effects but no analgesic effect either). Just prior to the current proposed regime that I have mentioned above, the latest combo was
Acetaminophen - 500
Naproxen - 250
and sad to say, like Gabapentin, no side effects nor analgesic effect. So we'll see what
Tylenol 3 - to be taken 4X / day
Naproxen 250mg - to be taken 2X / day
happens with the above.
"Therefore, sometimes extra fiber can exacerbate that situation". I can't understand why extra fibre would make things worse - that's kind of counter-intuitive. As for the homeostasis (that's nice word for tolerance), any idea as to how long that takes to manifest?

Jump to this post


Replies to "Thanks so much to both of you for your responses. I wrote that one of her..."

For the purposes of this discussion tolerance and homeostasis refer to the same thing, but there is a significant difference when getting technical. Regardless of the fiber variety, sufficient liquid is necessary for proper utilization in the bowel. Since narcotics stop the peristolsis of the large intestine any liquid necessary is not available, thus the fiber itself can become a blocking agent. That is my experience anyway (many others too)- take it for what its worth. Each person is an individual and therefore different in their responses.

Unlike popular opinion, fiber is not the answer for constipation. Water, water, water, water water. And for me, I use an enema bag when things are really bad from pain meds. It solves the blockage but to be honest, it does not solve the day-to-day need for a BM. I have found Senna to be helpful for the day to day.

Have you considered traveling for the surgery? There are many good healthcare providers internationally at reasonable prices and then a better timeline. Mexico? Portugal?