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@williamsjen

Thanks for your response. I am going to check if the skin discolorations is a vein issue. however Dr. did say that HU can cause the change in skin. I just ordered me a treadmill yesterday, I go to the gym about 3 days a week but, it is convenient at home. I asked her will she lower the dosage back to 500 mg she said we will watch and make a determination after she see me in 3 months..
Thanks again!

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Replies to "Thanks for your response. I am going to check if the skin discolorations is a vein..."

Fingers crossed that you can get HU dose down and lose some of the bothersome side effects!