Do you have nail discoloration or skin? I have heard of HU dark streaks in nails, but 6 yrs on HU, and I haven't noticed that. Yet. Skin discoloration is one I haven't heard. I do have foot tingles, prickles, and burning, but hemo told me that's a circulation issue and do exercise for lower extremities. So I have an exercise bike. Helps to keep my feet moisturized, soak in cool water, put feet up. Your platelets seem good. Will doc reduce HU dose for you?