← Return to Signaterra testing

Discussion

Signaterra testing

Gynecologic Cancers | Last Active: 4 hours ago | Replies (9)

Comment receiving replies
@val64

We've discussed Signatera recently in this conversation:
https://connect.mayoclinic.org/discussion/post-treatment-follow-up-for-clear-cell-endometrial-cancer/
It's also been discussed in many of the other cancer forums. Use the search function (click on the magnifying glass icon).

Was your CA-125 elevated when your cancer was still present? If so, it's unlikely that Signatera will be better than the CA-125 test, and will probably be less sensitive. (The people on the pancreatic cancer forum tend to see tumor markers go up before Signatera.)

Jump to this post


Replies to "We've discussed Signatera recently in this conversation: https://connect.mayoclinic.org/discussion/post-treatment-follow-up-for-clear-cell-endometrial-cancer/ It's also been discussed in many of the..."

I am a year post chemo for stage 3 ovarian cancer and requested the Signatura test to monitor for recurrence. My test came back positive but my CA 125 was only 10. My oncologist/surgeon immediately ordered scans even though I was not due for the screening for a couple months. CT showed enlarged lymph node so Pet scan was ordered and the node showed possible recurrence so I had robotic surgery to have node removed with in two weeks of scans. Now waiting for pathology report to determine what next. I definitely will be requesting follow up Signatura testing to see if it is still positive since the node removal. Had I not gotten the testing I would not have gotten the early scans. Lessons learned. Needless to say I am a huge advocate of the testing.