Has Anyone Had Dental Work (implant, extraction) and Not Gotten ONJ??

Posted by sebutler @sebutler, Mar 1, 2025

Having dental work -- specifically, a tooth extraction or an implant -- is supposed to be a risk factor for ONJ if you are on a bisphosphonate or other antiresorptive medication. I was wondering if anyone in this forum has had this kind of dental work but NOT gotten ONJ. My brother has been on Prolia for several years and had extensive dental procedures to extract teeth and put in dentures, but has not had ONJ. As you might guess, I am posing this question because of fears of taking a bisphosphonate after being on an anabolic agent (Tymlos). That is required to prevent loss of the newly formed bone.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

I was on Prolia for 10+ years and now on Reclast for nearly two. I had to have an extraction and bone graft about a month ago and was very nervous. My endocrinologist was not concerned and advised that the periodontist prescribe antibiotics. I have come through this without any adverse consequences.

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Thank you for sharing this information, mfitz41!! Reclast is a strong bisphosphanate, so I am happy to hear that you have had now issues. Like you, I am very nervous about this drug, recommended by my doctor -- in case I have to have a dental extraction, since I have very bad teeth :(. You must be so relieved!! Glad it worked out well for you!!

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I’ve had 2 teeth removed and 2 implants without issue.

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Thank you for this information. May I ask what drug you were taking -- one of the bisphosphonates? or Prolia? And for how long? Thank you!!

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I have been on prolia for five years. I need to have three teeth extracted. What is the recommendaiton for having that done and taking prolia?

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Profile picture for sebutler @sebutler

Thank you for sharing this information, mfitz41!! Reclast is a strong bisphosphanate, so I am happy to hear that you have had now issues. Like you, I am very nervous about this drug, recommended by my doctor -- in case I have to have a dental extraction, since I have very bad teeth :(. You must be so relieved!! Glad it worked out well for you!!

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Updating my post of several months ago. This week I went to my endodontist for a 3-month follow-up on the bone graft done post-extraction. He was delighted with the results of bone growth and pronounced that I was ready for the implant. I had it on the same day and he commented that the density of the bone was amazing. I was thrilled to hear this of course. I’m on antibiotics and Peroxyl rinse to avoid infection. In another 3 months I should be ready for my crown.

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Profile picture for mfitz41 @mfitz41

Updating my post of several months ago. This week I went to my endodontist for a 3-month follow-up on the bone graft done post-extraction. He was delighted with the results of bone growth and pronounced that I was ready for the implant. I had it on the same day and he commented that the density of the bone was amazing. I was thrilled to hear this of course. I’m on antibiotics and Peroxyl rinse to avoid infection. In another 3 months I should be ready for my crown.

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Good to hear!! Thank you for sharing,

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Had two extractions on TYMLOS and Reclast. No problem.

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That's great! Of courses, Tymlos should not cause any problems, but Reclast potentially could, since it is a bisphosphonate.

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