The chemo is in two stages. First you hold for 1.5 hours then void out and then they put the second in and you have to hold that for 1.5 hours and then void out. Suppose you could do it on the way but they recommend putting a bleach tab in toilet after doing so and letting sit 15 minutes before flushing. Maybe could do it at Mayo and then drive home. Warning chemo can make you feel pretty lousy! Do you have someone could drive for you? Good Luck.