You give a very detailed history. Let me just say I am 71 and was first diagnosed at 32 and have had radiation, chemo, 2 separate mastectomies surgery to my chest wall, lymph node surgery, cyberknife. I have been NED for the past 3 years & have had Signateta every six months for the past 2 years and am extremely grateful to do that rather than continued PET/ CTS. So worth it in my opinion.