Hi @rjperk633 Such a lovely update about your mom! Wishing her a belated 88th birthday. I’m glad she’s continuing to feel well, eating normally and really, all things considered, not having any complaints!

The itching and the spots could be signs of progression. As her platelet levels drop, she may be more susceptible to brusing and more ‘dots’. Look for signs such as nosebleeds, or prolonged bleeding from cuts. There’s not much to be done if she’s electing not to have treatment but she’s doing great so far!
Also, keep an eye on her with the Benadryl. It is a first generation anti-histamine that can actually cross the blood/brain barrier. Recent studies have recommended reduced usage with older patients for risk of dementia symptoms. At least with children’s benadryl, it’s liquid so less than the recommended dosage can be used.

Her next blood work will be informative. She’s happy and comfortable…that’s the main thing! We may have talked about this before, but would she consider platelet or blood transfusions if the levels became seriously low?