I have had 3 procedures for my MALS The first was a major open surgery. A little over a year later, they wanted to do a bypass but I was not healthy or strong enough so they put stents in celiac and SMA artery. I was rare since my sma was involved. Then I had a balloon in my celiac. It is now narrowing again. For me, this is going to be a life long thing. For many though, I have seen people have even laparoscopic surgery and eventually they are fine. These people usually have the compression and nerves taken care of . Every person is different. It is definitely possible to have one and done. It all depends on your situation. Honestly more often there are more than one surgery, but there are people with one and are fine.