Has anyone ever been on Duloxetine (Cymbalta) for nerve pain?

Posted by dougs72 @dougs72, Jun 22, 2024

Has anyone ever been on Duloxetine (Cymbalta) for nerve pain? I've had 2 doctors push this on me. I know that the side effects can be terrible and getting off of it difficult as it requires titration. One time I remember taking one pill, and not liking the way it made me feel, so not taking any more, and still feeling the "weirdness" from it 2-3 days later. and that was only 30 mg Please pass along any experience or advice from this medication?

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I have used Cymbalta 60 mg twice a day and gabapentin 800 mg 3 times per day for some time. They do help a lot

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I was given duloxadene for arthritis but after a month I developed uncontrollable vertigo and had to slowly withdraw from the drug. I believe it is a harmful drug that alters the brain's ability to recognize pain but alters the brain's ability to control emotions or recognize reality

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@marialyce

What kind of pain did you have?

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I tried cymbalta and could not take it . Too many side effects, the last being loss of vision.

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@dougs72

how is lyrica different and what is it prescribed for? Where are you getting the burning?

The symptoms were a bit of nauseous, but just a weird headache (sides of the head for some reason) and an overall blah and foggy feeling. I also heard that there is "brain zaps" fairly common in folks. This may be related to those feelings. It's hard to describe, but it wasn't pleasant at all. I also heard that it's bad for the male libido (delayed or no ejaculation, etc...) and that is fairly common side effect. All in all I'm not looking forward to it if I try it at all.

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Many drugs have the side effect of destroying a men's libidos. My husband has been on Neurontin and Cymbalta for foot Neuropathy for over 20 years now and sex went out the door along with the start of the meds. He tried other "helps" from shots to pumps, but nothing worked. He can't even get a partial hard-on.

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@marthadean

I was given duloxadene for arthritis but after a month I developed uncontrollable vertigo and had to slowly withdraw from the drug. I believe it is a harmful drug that alters the brain's ability to recognize pain but alters the brain's ability to control emotions or recognize reality

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I was prescribed Duloxetine for Shingles pain but it was not worth the price of my titrating off it. Did you get brain zaps when you first went off it? I only took it for a couple of weeks but had to taper off it for over a month the brain zaps were so unpleasant! Some people take up to a year to get off it. Other drugs like SSRIs and Lyrica can also cause impotency in men and are equally difficult to get off.

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I tried Cymbalta several decades ago for depression. I had to discontinue it due to severe irritation in my stomach. It felt like it was on fire. I commented because Cymbalta seems to work for some but not me. Good luck and happy living

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@dianeflorida

Cymbals made me feel great but caused low sodium and some side effects from that

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I had been taking it for a couple of years, but diarhea, terrible stomach cramps each time I take it had gotten so bad. Between that and taking ibuprofen or Tylenol daily for leg and ankle pain for a broken, collapsed ankle before ankle implant surgery.....I couldn't sleep at night because of the pain. I was put in the hospital for bleeding ulcers and pancreatitis. I think the Tylenol and ibuprofen every 4 hours did the most damage. I could not get prescription pain medicine for chronic debilitating pain and I was eating OTC meds like candy. and they only took the edge off. Now the duloxetine feels toxic for me. It always caused an indigestion feeling. I don't know what to do for my chronic pain, stiffness, lymphadena and neuropathy now and my doctor won't change the duloxetine to something else. I would like to know if anyone has this problem and if they found help. Another thing, my large intestine was removed when I was 28, I am 72 now. Many years of pain, gut problems and feeling awful.

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Yeah it didn't help at all I have spondylolithesis good luck

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@celia16

I share your concern. I have the bottle of meds in my cabinet. I’m preparing to start it. Dreading it….but I have to try it, before my insurance will cover Lyrica.
And, Cymbalta may actually serve me better. Idk.

I’m ambivalent. I’ve read so much about it. Different people have different experiences. What I know is that my intermittent burning is excruciating and I can’t tolerate it long term. I’m scared and looking for answers, since my only diagnosis right now is Vitamin B12 deficiency.

Klonapin does help, but that’s a short term thing. If my burning continues, I’ll need something daily. I wish there was something to take on as as need basis, that’s not a Benzo, since I feel great on days there isn’t burning.

When do you think you’ll start and what symptoms did you have trouble with?

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It was awful for me. Bad NAUSEA, and a drugged feeling, needing to lay down, and a headache.
I'm....not....going....to....take....it.
All the drugs affect me badly. Gabapentin will give you leg and toe cramps, bad ones and make you feel like you are drugged all the time.
I do know people who can tolerate Gabapentin well, just not me.
I hate nausea. So they are both off the table for me!

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