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Next Steps?

Hypertrophic Cardiomyopathy (HCM) | Last Active: May 25, 2025 | Replies (14)

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Correct/ it’s for diabetics but recently through clinical tests for some Empagliflozin (Jardiance and other trade names known as a SGLT-2 in inhibitor) was discovered that it promotes active relaxation of the heart and improves diastolic dysfunction (DD) in many. They don’t know entirely why it works for DD. It wasn’t developed for it. I guess it’s kinda like how Viagra was produced to control blood pressure but helped something entirely different. I’m at my wits end so I’ll try anything at this point.

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Replies to "Correct/ it’s for diabetics but recently through clinical tests for some Empagliflozin (Jardiance and other trade..."

Lab work good. Testosterone - not sure. I generally feel crappy the day after I exercise. How thick is your septum? Mine is 1.8cm/ 1.9cm depending on the tech.

I have Apical HCM (non-obstructive). So, I have diastolic dysfunction, an aneurysm on the apex of my left ventricle. Then two years ago, I presented with persistent AF with RVR. And, I was very symptomatic. After trying rate control, which didn't work, I am now on an antiarrhythmic medication (dofetilide) which worked great for about a year. Then I started having occasion breakthrough episodes. In February of this year my HCM cardiologist at Mayo Rochester started me on Jardiance because I continued to have symptomatic AF breakthrough. He hopes it will lower my filling pressures and "fine tune things from a diastolic standpoint." Don't see him until September so not certain it is helping, but have not had a breakthrough so fingers crossed.