I am so sorry to hear this. Steroids/prednisone usually only cause those symptoms when weaning of or attempt to discontinue. In fact, I was placed on prednisone due to the joint pain and inflammation in discontinuing Dupixent. You are in my shoes from back in 2019, but there is plenty of information available on this adverse reaction to Dupixent now. I urge you to look into Dupixent causing joint inflammation/pain, seronegative arthritis, feeling unwell, etc. It is also listed on Dupixent official website that it can cause these symptoms. Cut and paste some of these into your browser. There are many sites which list arthralgia/seronegative arthritis as a side effect. https://www.drugs.com/medical-answers/dupixent-joint-pain-3552823/ https://www.dupixent.com/frequently-asked-questions https://www.aaaai.org/allergist-resources/ask-the-expert/answers/2022/arthralgia https://www.reddit.com/r/eczeMABs/comments/zc89hc/dupixent_and_joint_pain/?rdt=61993 https://pmc.ncbi.nlm.nih.gov/articles/PMC8814740/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8814740/ I hope that when/if you do decide to discontinue Dupixent that your symptoms disappear and that you are not left with any permanent damage. May I ask for what diagnosis are you taking Dupixent?