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Anyone have experience with Dupixent for asthma?

Asthma & Allergy | Last Active: Dec 6, 2025 | Replies (62)

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In July 2019, my pulmonologist prescribed Dupixent for severe asthma. After 2nd injection/dosage, I began having extreme joint pain (most everywhere) to the point I could not walk for months without assistance (crutches, cane, etc.). The onset was so quick, and I immediately discontinued Dupixent. Over the next few months, I did research and contacted the Dupixent 800# to determine if Dupixent could cause arthralgia. Nothing at that time revealed a link between Dupixent and arthralgia/seronegative RA. In November 2019, I underwent diagnostic testing with a rheumatologist, and at that time I was diagnosed with seronegative RA. I would only find out later than in January 2020, NIH revealed that there is a direct link between Dupixent and arthralgia/seronegative RA which is still available on NIH website and various other sources. Since then, I have had 7 surgeries to include double total knee replacement, RFA, etc. and more in my future. There is so much more to my story, but I will not bore you. I'm not saying that everyone will have this side effect, but I do believe it is definitely worth mentioning.

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