I started chemo/immune treatment for WM in March & developed a bad rash following 1st treatment. 2nd treatment only got 1/2 way thru due to rash. I found that Clariton plus a medrol pack & lots of lotions (including Cortisone cream, benadryl gel, lubriderm, aloe) gets it under control w/in a couple days. 1st couple days are
misery. I did just the Bendamustine for the 3rd round to see if that's what I was reacting to & it was. I don't know if I'll also react to the rituxan (haven't been able to make it through entire dose yet due to infusion reactions). Next treatment may be just rituxan to see. I read if you get rash with Benda it means your body is really responding. My IgMs have gone down from 3850 to 665 with just 2 1/2 treatments. I'm hoping I can continue treatments with prophylactic clariton prior to treatments. I'm sure the rash will still be bad but hopefully controllable. Also the rash in later treatments were not as bad as after the first treatment. Best to you in your treatments!