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Anyone familiar with the clinical trial RMC-6236? Or how to enroll?
Pancreatic Cancer | Last Active: May 24 7:16am | Replies (34)Comment receiving replies
Could you try and get into a trial of just the 6236? City of Hope in Irvine (CA) is hoping to get this soon. If you could travel for initial setup you could continue your care back in Florida. Dr.Kasi at Hope will be in charge of that trial. Or there’s the Naliri chemo available which I’ll be starting next week unless radiologist were to set up my SBRT first.
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@mnewland99 , Thanks for the info. Do you have the NCT trial # for the one at COH?
The only ones I'm aware of w/ RMC-6236 are either Phase 3 (randomized; not going there) or in combination w/ other SoC chemo drugs that I haven't already had.
Even though 6236 is an oral med I could take at home, I don't think I could get into a trial at COH without frequent travel back to CA since they want to measure absorption rates and blood concentrations -- I doubt I could find a local lab/provider willing, capable, or approved to do the tests that study requires.
The only SoC drug I haven't tried is Onivyde (the new nano-liposomal irinotecan). I asked my onc today if I should switch to that as a bridge until I qualify for a trial. I was advised not to, because the likely failure/progression on another line of therapy would jeopardize my chances of getting into a trial with more promise.
I'll be getting tested for expression of CLDN18.2 soon, and checking into other studies. There are some KRAS G12D trials with drugs other than RevMed's.