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Developed Rash on Hydroxyurea (HU)

Blood Cancers & Disorders | Last Active: Oct 17, 2025 | Replies (26)

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I take both 500 mg of HU capsules at night, just before bed. I periodically have itching over area of my right shoulder blade and tops of my hands. I’ve used lotion with some relief, and a back scratcher. And, now and again a prescribed cortisone cream. But, you made me think that maybe it’s the generic equivalent of Claritin that I take daily for sneezing that may be helping keep the itching controlled. I never thought about it before.
Benadryl makes me sleepy so I avoid it.
If you can, maybe sub the Benadryl for Claritin or generic?

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Replies to "I take both 500 mg of HU capsules at night, just before bed. I periodically have..."

Agree with the itching...this article made me chuckle because I asked my kid to get me a back scratcher from Walmart just this week! I have good luck using gold bond for diabetics anti-itch lotion. I am not diabetic, but the lotion is great and helps when it's bad I use hydrocortisone topically.