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Orgovyx side effects and handling them

Prostate Cancer | Last Active: 6 days ago | Replies (45)

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@colm

I have just been put on Orgovyx , I was diagnosed in February and not seen an Oncologist yet. Trying to find out what to expect and to find out how well Orgovyx holds back the progression. I am fortunate that my PC is contained in my Prostrate. Any info would be greatly appreciated.

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Replies to "I have just been put on Orgovyx , I was diagnosed in February and not seen..."

You are in the same boat as me, more or less.
With a median follow-up of 51 months, the 5-year PSA relapse-free survival for men with low-risk PC was 92% with the addition of ADT vs 84% without ADT (P = 0.09). The issue of RT–HT in low-risk PC patients was also indirectly addressed by a retrospective analysis conducted by Ciezki et al.28 The study included 1,668 patients with low- and intermediate-risk PC treated at The Cleveland Clinic Foundation with EBRT, RP, or prostate brachytherapy with or without androgen deprivation during 1996–2001. The 5-year biochemical recurrence-free survival (BRFS) rate was 90% vs 93% for EBRT alone or with ADT in low-risk patients.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3004567/#:~:text=Specifically%2C%20the%20overall%20survival%20(OS,CI%5D%3A%200.83%E2%80%931.39).
Those are pretty good odds , I'd say.

I have experienced all the "common" and "other" side effects except constipation, and I have been on Orgovyx five months. With this med and 44 radiation treatments during February-April, my PSA has dropped from 6 to .11. I have more tests this week and anticipate the PSA will continue to drop. The system here won't let me post the link, but if you'll go to Orgovyx dot com and click the "About" tab, the last item is "side effects."