← Return to Testosterone- confused

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Testosterone- confused

Prostate Cancer | Last Active: May 22, 2025 | Replies (19)

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I'm now 73, took only 4 months of Orgovyx but that was plenty to mess up my system seemingly forever with the 4 main symptoms: Hot flashes, ED, weak/tired and belly fat. My pre-ADT T was 467, post-ADT 32, then 12. All my Drs., from two major institutions, had said that after one year, if my T doesn't recover to the normal range they'd consider adding some. In Jan. 2025, I was still at 152 and started talking to a couple fertility urologists. Around March, after consulting at least 5 ROs and urologists, I started daily 5 mg. cialis and T Gel, Testosterone 1.62% Gel, 2 pumps per day. He also added a lot more test, like lipids, into my quarterly monitoring. In April, my T rose to 427 with Free T at 44. All the major symptoms immediately improved, however, I still had a few hot flashes. In my last consult with the fertility urologist, I asked about getting off the drugs and he said that it's unclear how the symptoms would return. I found when I stopped T Gel, I got a quick return of all symptoms, some with vengeance. So, I decided to try one pump per day and that seems to be better, but I won't know my actual T reading for another 2 months. Hopefully, my body can do the job on it's own and my PSA stays very low.

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Replies to "I'm now 73, took only 4 months of Orgovyx but that was plenty to mess up..."

I'm still in my early 60s but my experience is similar to yours. Three months after stopping Orgovyx my T went up into normal range but three months after that it dropped well below low normal and I started getting bad side effects again. I was told if it continues to drop they will supplement. We'll see.

After 2 yrs, at age 75, my T returned to pretreatment baseline level.

No actual medical advice, but here is my T history after Salvage Treatment of IMRT radiation and 4 mos Orgovyx:

73 - 1 T test pre salvage ADT 439 (baseline)

Orgovyx dropped T to less than 2.5

9 mos post Orgovyx T 349 - 335 (quarterly testing 4 times)

Most recent 2 T tests 417 - 482

I don't know why T recovered about 75 - 80% for about 1 yr and then "popped" up to pretreatment level.

Confused, grateful and concerned.

Status quo for PCa victims.

Best wishes.