Here's a response I made a while back, much on it is valid for your question: https://connect.mayoclinic.org/comment/1292044/

For the catheter, I found having sanitizing wipes for keeping the tip of my penis very clean to prevent any problems as well as lubricating the catheter with some medical grade lubricant helped keep things more comfortable. In fact, the only discomfort was the 2 seconds they removed it, other than just the annoyance of having one in.

I also found breakaway pants to be absolutely fantastic for this period of time!