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Anyone seen research on long term Proton Pump Inhibitor use and PN?

Posted by blearyeyes @blearyeyes, Aug 16, 2023

Anyone seen research on long term OTC Proton Pump Inhibitor use and PN?

I just read an article (on the internet) about anecdotal evidence of long term use of over the counter PPI use as a cause of Neuropathy along with a bunch of other issues.

I was told I would have to take PPIs for life for GERD by an Gastroenterologist 15+ years ago. Now they are saying don’t take more than 2 x 14 day runs a year.

Interested in more discussions like this? Go to the Neuropathy Support Group.

deserthykr | @deserthykr | 22 hours ago
In reply to @bigjohnscho "I have a very unreceptive GP who doesn’t respond well to questions. He seems to regard..." + (show)
@bigjohnscho

I have a very unreceptive GP who doesn’t respond well to questions. He seems to regard them as challenging his authority

John

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Can you find another doctor for yourself?

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lindavs | @lindavs | 22 hours ago
In reply to @bigjohnscho "I have a very unreceptive GP who doesn’t respond well to questions. He seems to regard..." + (show)
@bigjohnscho

I have a very unreceptive GP who doesn’t respond well to questions. He seems to regard them as challenging his authority

John

Jump to this post

Please consider changing doctors. I had been on medical literature for many years that PPI,'s should only be used on a temporary short term basis. BTW, have you ever been tested for celiac disease. Requires an endoscopy and blood tests, which should include (if you have a really good gastroenterologist.) I was told for years that I had GERD and was put on a PPI for a number of years. He retired and I got a much younger gastroenterologist. He immediately started weaning me off PPI and scheduled me for an endoscopy. Turns out I had celiac disease. Do some research on celiac on this site. You may indeed have something other than celiac but it is often misdiagnosed in adults.
By the way, I have PN in both feet and legs, to just above the knees. There is a link between celiac and neuropathy as well. Mayo main website also has lots of info on issues re: PPIs.

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lindavs | @lindavs | 22 hours ago

This is an article written for medical professionals but much of it is understandable. Worth a persistent read.
https://www.mayoclinicproceedings.org/article/S0025-6196(17)30841-8/fulltext

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bigjohnscho | @bigjohnscho | 1 hour ago
In reply to @johnbishop "Have you been tested for vitamin B12 deficiency? You might want to check with your doctor..." + (show)
@johnbishop

Have you been tested for vitamin B12 deficiency? You might want to check with your doctor to see if the long term PPI usage is affecting your B12 level.

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John, I would like to start taking RALA but when I tried it before, although I felt some benefit it upset my stomach. Is there any way I can solve that problem. I was only taking 200mg

John

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