Hi all who need Xarelto , I have been taking Xarelto 15 mg. daily for going on three years now. I take it for Lividoid Vasculopathy, because thinner blood helps LV ulcerations from forming especially on my feet and ankles. I have had procedures that have d/c xarelto for a few days at a time. I have not noticed any particular pain associated with being off the drug . Have you checked with the Mayo pharmacy about this? They are very helpful and take more time with their research than your local pharmacy. Good luck, Zenk Are you taking anyother med that may account for this?