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Has anyone used the Marodyne device to stimulate bone growth?
You stand on it twice a day for 10 minutes. It gently vibrates and also helps with improving balance. The Marodyne is made in Germany and costs about $3,000. It has not been FDA approved but there are studies in progress.
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My last endocrinologist wanted to put me on Reclast, prolia and every drug under the sun for about six years and I refused. On our last visit, she said if you don’t do what I say then I can’t help you…. so that was our last visit. As I walked out the door, she said don’t break a bone. I guess that was her sense of humor? I will not mention the name of the doctor, but she is highly rated in a large hospital in Philadelphia. I now have a new endocrinologist who is willing to work with me and my choice to do bioidentical hormone replacement therapy. If your doctor is unwilling to seek answers find someone else!
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3 ReactionsThis is so typical of healthcare in the USA! I found out about trabecular bone from Margaret Martin, who is Canadian...now living and consulting from Portugal. Her website is invaluable for osteoporosis patients. "If your tool is a hammer, every problem's a nail," goes the saying. U.S. docs "tools" are pharmaceuticals and knives (surgery) for fixing problems. Most don't take lifestyle, what we eat, etc. into consideration. And they probably don't have time to do so--they are burdened with "paperwork" viz a viz punching data into their screens during our appointments. So yes! Read McCormick's book. Check out Margaret Martin's site: melioguide (dot) com
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6 Reactions@nme1985
What an unprofessional comment coming from a medical professional. So happy you found and endocrinologist willing to work with you!
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2 ReactionsHi @madhub140
Where is the video please?
Thanks!
The scientific papers on the list below (this list -- from Marodyne's site -- should give you an idea of how much research has been done on low-intensity vibration. )
If you find Clinton Rubin on Google Scholar you'll find a list of research papers -- click on "year" to find the most recent.
The web page of Clinton Rubin at Stony Brook University also has explanation of the research that led to the development of the device, as well as research conducted using the device.
Unfortunately I cannot include links to websites in this message, as I am a newcomer to this community.
FROM GOOGLE SCHOLAR LIST OF ARTICLES:
The Effect of 9 Months Whole Body Vibration, With or Without Osteogenic Exercise, on Indices of Bone Strength and Fracture Risk: the VIBMOR Trial
B Beck, C Rubin, M Forwood, A Harding, L Buizen
JOURNAL OF BONE AND MINERAL RESEARCH 38, pages 371-371
A FEW ARTICLES FROM MARODYNE (go to "Osteoporosis" and pull down to "Studies")
Studies related to LiV
Peer-reviewed studies have been featured in leading scientific journals.
'Mechanical signals promote bone and muscle anabolism while limiting formation and expansion of fat mass. Mechanical signals, such as those induced through low-intensity vibration, need not be large in magnitude, or long in duration, to influence bone or fat phenotypes'
Gabriel M. Pagnotti, Maya Styner, Gunes Uzer, Vihitaben S. Patel, Laura E. Wright, Kirsten K. Ness, Theresa A. Guise, Janet Rubin & Clinton T. Rubin. Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity. Nature Reviews Endocrinology (2019)
LiV signals help childhood cancer survivors with bone density Kirsten K. Ness, The effects of low magnitude high frequency mechanical stimulation (LMS) on bone density in childhood cancer survivors (CCS), Podium Presentation, APTA CSM Indianapolis Feb 2015
LiV signals may prevent osteoporosis Ward, K. et al. Low magnitude mechanical loading is osteogenic in children with disabling conditions. J. Bone Miner. Res. 19, pages 360 to 369 (2004).
LiV signals strengthen long bone Rubin, C., Turner, S. Bain, S., Mallinckrodt, C. & McLeod, K. (2001) Anabolism: Low mechanical signals strengthen long bones. Nature 412: pages 603 to 604.
LiV signals can improve postural stability Jesse Muir, Stefan Judex, Yi-Xian Qin, Clinton Rubin: Postural instability caused by extended bed rest is alleviated by brief daily exposure to low magnitude mechanical signals Gait & Posture (2011) pages 429 to 435
LiV signals accelerate and augment bone repair Goodship AE, Lawes TJ, Rubin CT.: Low-magnitude high-frequency mechanical signals accelerate and augment endochondral bone repair: preliminary evidence of efficacy. J Orthop Res. 2009 Jul;27 (7):pages 922 to 30
LiV signals can improve bony ingrowth of implants Rubin, McLeod – Promotion of Bony Ingrowth by Frequency-Specific, Low-Amplitude Mechanical Strain – 1994 Clin Orthop Relat Res.
@healthmatters
May 4, 2025
I concur with you - if Marodyne was science based we would not be
here discussing it, and discussing it again.
We are so vulnerable and at times ..fearful, yes at times, the word
is fearful,
which makes us very susceptible to marketing messages,
and we will try most anything and everything.
About the Peer Reviewed studies on Marodyne, can someone link
a clinical study that does not have Dr Clinton Rubin's name on it.
Please share it with us.
I - always - look at the bottom of clinical studies to see the names
of professionals involved in the study, as well as conflict of
interest, such as grants from pharmaceutical companies.
I asked my physiotherapist about Marodyne.
He provided me with a xerox copy on study of whole body
vibration He says many PT and OP are guided on information
found on meta analyses.
You can go to Elsevier and download
Systematic review and meta analyses on the effects of whole body vibration on bone health.
It is a meta analyses. It is dated 2022, and downloads to your
computer as a zip file which opens quite easily.
It is difficult, to translate that data, technical stuff,
to real life decisions on what to buy.
As of now, approx 2 years after my diagnosis for 'severe
osteoporosis' - I still have not decided to take - or not to take
any drugs -
My very first appointment was with a young doctor,
a geriatrician I think, who walked into the room with a notepad
and in dulcent tone of an undertaker said - you have very severe osteoporosis.
Next came fear, and fear, and anxiety.
I then saw an older Endo who warned me I could be in the
30% who die within 2 years if I broke my hip. And why would I not
take Evenity, he asks, you haven't had a heart attack, have you,
discounting the possibility of cardiac events.
Don't make the bed - I said to myself, because someone fractured
doing that.
Don't lift that heavy water kettle - I said to myself - someone mentioned
fracturing.
Don't don't don't...reinforced by all those youtube videos..
I looked at so many on youtube..Margaret Martin and plenty of others.
One size does not fit all.
I was not..and did not have a recent history of fracturing.
And wondered...can I heel drop safely...can I lift weights over my head safely.
How heavy...
Sadly, it is hard to find - one clinic with Comprehensive locus for osteoporosis
patients to get information on everything we need to do to help bone density:
execize, including balance
nutrition.
and vitamins/supplements.
drugs, if you find it necessary.
When it comes to nutrients and supplements, it is so time consuming.
Each one of us has to find out what supplement, what nutrient
would help bone health.
Think of the time spent, searching for answers.
The advice most readily given to us is drugs.
It takes a lifetime to do research on each supplement or each nutrient,
delaying the optimum time to take them.
Nutrition, exercize and balance has been my focus for the past year.
I had a Dexa two week.
My spine improved 5.6% My hip improved 6.4%
My goal is to improve on these scores.
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4 ReactionsI have been using the Marodyne device for two years . No benefit at all so far and I now have dizziness.
Congratulations on your Dexa improved scores! Impressive that you could do that with bone drugs! I have been on Tymlos for 5 weeks - I delayed starting out of fear of the side effects. So far so good.