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P1NP decrease with 9 month drug holiday

Osteoporosis & Bone Health | Last Active: 17 hours ago | Replies (12)
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@mayblin

Thank for sharing @dooshie. P1NP reading of 19 in your case doesn’t mean you are losing bone. When you are on HRT, estradiol suppresses osteoclasts’ function so very likely your CTX will be pretty low. It won’t be surprising to see CTX at 200s even 100s --you will soon find out! With a low CTX, your bmd gained with tymlos will be preserved unless there are other reason(s) for bone loss.

You could decide after next Dexa to see if you need further bone building. I’m not sure if prescribing second round of tymlos is a common practice now or whether insurance will cover another round of it. However, nothing should be in the way to have Forteo or its generic for you.

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Replies to "Thank for sharing @dooshie. P1NP reading of 19 in your case doesn’t mean you are losing..."
dooshie | @dooshie | 17 hours ago

@mayblin…thanks so much for ur reply. I was a bit devastated when I saw my P1NP number and I did get my CTX back yesterday and it’s 153. You’re much more educated with these numbers than I am so any info is greatly appreciated. I don’t have another dexa till the end of the year so we’ll see then.
I knew it was very possible that my numbers would drop after going off Tymlos but I had hoped the bio hormones would hold them.
I’m extremely active playing pickleball, lifting weights, jumping, heel stomps, so I hoped that would help. I’ve never fractured but I do try to do everything with great care that I don’t fall.
Thanks so much for ur reply. Have a great day! Rose 🌹

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