sue417,
so sorry you fractured. Radiation works on our cancers because it disrupts DNA, but it does the same with the bone in the line of the radiation vector. Trabecular bone the bone in our spine is most vulnerable.
The antiresorptives, like Reclast, make it difficult for damaged bone to self repair. The three years of Reclast may have played a part in the fracture.

Tymlos and Forteo have a different way of increasing bone density. They increase our bodies ability to remove damaged, fissured bone and increase the cells that replace the bone with new bone.
Both Tymlos and Forteo are analogues--that is similar in structure to part of pth ( forteo is recombined dna, tymlos is snythetic) They are considered homogenous in the first (1-34) amino acids that comprise the parathyroid hormone.
So they both work by increasing parathyroid in the blood by injection, but only for a brief period of time. They basically trick your body into thinking you are losing bone, so that your body immediately produces the cells that break bone down and the cells that build fresh bone.
Tymlos attaches to a part of the protein receptor that Forteo doesn't prefer . Because of that attachment Tymlos isn't active as long as Forteo, which works even better. Tymlos produces fewer of the cells that break bone down. You are less likely to have hypercalcemia with Tymlos than Forteo. And it is thought that, especially in the hips, the bmd results are slightly better . The Tymlos dose is higher 80mcg vs Forteo 20mcg. And Tymlos contains a preservative that some are allergic to.
Many doctors have no preference for one over the other and just prescribe whichever insurance will pay for.
I'm often enough unclear. I'm happy to try again.