Welcome to Connect, @cmlsux. I’m mystified why your oncologist is so dismissive with the side effects of your CML treatments and suggesting that your GP will handle those. That’s out of the purview of most GPs. I’m so sorry you’re having this experience. The side effects of some of our blood cancer meds can certainly mess with our daily quality of life.

There are several potential options for CML treatments. It isn’t out of the ordinary to try another medication if the side effects from what you’re taking are too debilitating.

Frankly, with the attitude of your doctor, I’d seek a 2nd opinion if you have that option. I’ve worked with several hematologists oncologist over the years. And even the doctors who were on a tight schedule still made sure my side effects were addressed, if not by them, by their NPs. It’s part of the entire package. Your doctor feels mechanical/clinical. We don’t have to be best friends with our doctors but we do need to feel a level trust and empathy from them.
I’m glad you finally got anti nausea meds. Some work better than others so if what you’re taking isn’t helping, ask for another. The sublingual Zofran tabs worked really well for me, taken right before meals. But any anti-nausea med can also slow down the normal peristaltic movement of the gut and sometimes cause constipation…just to keep that in mind. If you can, drink at least 64+ ounces of room temp water daily to help flush toxins. That can also help the gut.

Another thing that helped my lower digestive tract tremendously during chemo was daily Greek fat free yogurt with a small amount of flax. Seemed to calm things a little and keep my gut healthy. Not easy to do if you’re nauseated.

I have a good article from Dana Farber that might be helpful to read through for managing digestive issues during/after chemo. https://blog.dana-farber.org/insight/2023/03/how-to-manage-digestive-issues-during-and-after-chemotherapy/

What is your current treatment for CML?