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PSA numbers after radiation with no ADT
Prostate Cancer | Last Active: Sep 17 3:12pm | Replies (33)Comment receiving replies
My SBRT has been a roller coaster. 3 opinions on biopsy. 2 said 3+4 W/cribiform. 1 said 4+3. W cribriform
Pre-treatment PSA was 9
Post-treatment:
2 months, 11.96
3 months 9.25
7 months 4.83
10 months 6.38
12 months 6.02
14 months 5.41
17 months 3.9
Test again in June.
I was the guy who had the post-radiation inflammation spike.
Then the radiation “bounce”
All doctors involved think its going well though.
PSA kinetics without ADT are unpredictable. But the thing I keep being told is that as long as it is dropping it is working.
The reason for no ADT was that I had limited positive cores 4/15. All in one area. And MRI showed a smaller than usual lesion. 3x3x7.
I'm treated at a major cancer center and my Dr said he expects it to nadir at about 1 in 2-3 years. Hopefully get to the .5 level but I have BPH and a history of prostatitis.
Replies to "My SBRT has been a roller coaster. 3 opinions on biopsy. 2 said 3+4 W/cribiform. 1..."
Your case is very interesting. I agree that given all your data points prior to treatment, your path was a good one.
I would have almost certainly made the same decisions you did.
Would you mind giving an update to your situation? PSA wise?
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There seems to be a lot of individual variability in PSA numbers. Your trend is a positive one and bounces are usually associated with better outcomes. Any reason why you are having tests so frequently? They are usually stressful events for most folks. I have decided to go to a longer interval between tests.