No, low iron issues but I’ve been taking prescribed Folic Acid since I started HU. Once my hematocrit level more or less remained at 42 or below (my “sweet” spot, the PA suggested I stop the Folic Acid. I told her everything seemed to be working just fine and I was not willing to make any changes if there was no harm in continuing with it, She agreed. Maybe ask your caregiver about Folic Acid?
And, I think you are a cautionary tale about taking supplements. I always research and then still ask the doctor. I wanted to take a collagen supplement for my hair and when I asked she told me it would change lab values!