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Any concerns if you have MGUS and need joint replacement surgery?
Blood Cancers & Disorders | Last Active: Apr 28 3:34pm | Replies (10)Comment receiving replies
I have had four joint replacement surgeries since diagnosed with MGUS in 2002. This included two knees, a hip, and a shoulder. All surgeries went very well; they were done at Mayo in Rochester.
I put off having the knee replacement surgeries because I was afraid of progressing. The hip was necessary - could not walk.
All surgeries affected the free light chains. The last surgery (shoulder) increased these FLCs the most. My M spike did not increase. My involved lambda over not involved is now 15.3. It has decreased since after the surgery when it was 17.
I hope this is helpful.
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@hsminc
what a coincidence, I just got hip replacement on April 1. I know… It is sort of a challenge to the gods of MGUS to get hip replacement on April fools Day. Many friends reminded me that this was a challenge worthy of a much younger person. I got hip replacement in 2016 and it went so smoothly. Same surgeon same hospital fast-forward to 2025. I don't know if it had anything to do with MGUS, but I had a really rough first week post surgery. Pain medication typically makes me nauseated so I avoid it and I took very little of the prescription medication. I truly did not have a lot of pain but I was nauseous for that first week. Even the thought of food or the mention of food was enough to trigger a response. I'm almost 10 years older than last time so again, I don't know the cause.
Day eight I decided I'd had enough of that and I was going to eat regardless. So I did and began to feel better. Since then, I have had what I would describe as an easy recovery. It is annoying to me to have to use the walker but my surgeon insists that I do for six weeks and then six weeks on a cane. Since he's the bees knees of hip replacement and knees I will comply. he will be quick to tell you that he did Terry Bradshaw's knees and it is almost as though one has to request an audience to get an appointment. He is good though and I've had absolutely no complaints about my other hip.
So now I have a matching pair and I can endure twice the scrutiny at airport screeners. Yay!
Best of luck with your surgery. When your hip tells you it's time… It's time. I don't have an appointment with my hem/onc doc until July so we'll see how the numbers go but I feel good right now.