Well, I’ve been taking it for about 5 years for PV. I’m 77. I’d love to say the fatigue was temporary but, for me, it’s not. I will tell you that it comes and goes, mostly comes. However, a month or so ago my MD found my thyroid med needed to be adjusted. After starting new dosage I felt like someone had started my motor and not only wasnt I tired, I had energy to want to get things done! I was a dynamo for about two weeks and then not.
As I’ve mention in other posts about HU it is, for me, the prevalent side effect but I think I’m also 77 years old and I attribute a lot of my physical problems to that or in combo with that.
Hmm, brain fog huh? Well, most days I think I’m as sharp as I ever was just slower sometimes to get to point. Bit, again, I have a tendency to think my age is the culprit before I put it on the HU. And, does it matter to me where to put the “blame”? Not really unless they come up with something better than HU that keeps my hematocrit, etc.where it belongs and me out of Infusion Centers for phlebotomies!
But, everyone is different and I haven’t had the headaches, itching (just occasionally and then a back scratcher takes care of it) and more intense reactions. And, for that I am grateful.
My suggestion is to just pace yourself and do what you can to adapt to the fatigue whether it’s temporary for you or not.