Hi all.having been diagnosed with two mutations jak2 and calf ihave been on double dosage of hydrea also injection to stimulate bone marrow into producing healthy cells...felt absolutely dreadful for past two weeks today had my visit turns out my haemoglobin has dropped to 8.6 so going in for blood transfusion next week..good news my platelets have come down from.700 to 450..adviced to drink plenty water..so hopefully transfusion will help