Anyone having luck while taking methotrexate?

Posted by lindaadele @lindaadele, Mar 23 4:57pm

I have been on my third week of methotrexate tablets. I take 5 mg each week. So far every medicationI have been taking for my PMR are not working very well for me they work until they don’t work!!! Right now I feel worse taking this medication then I did before I took the medication !! Any information that you can give me would be very much appreciated as I am really getting pretty frustrated with this whole PMR thing which I have had since April 2023. Thank you very much for any help that you can give me at all!!!

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@hammock117

I have been on Methotrexate and Hydrochloriquin for several years...gradually increased Methotrexate to 7x 2.5 mg.
I did not know about autoimmune vascular issues..

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Please tell me more. Are you saying the Methotrexate has created vascular autoimmune conditions for you?

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@lindaadele

I have been on MTX for three weeks. I am also on hydroxychloroquine . One day a week I take 10 mg of MTX dividing the dose up. I also take the folic acid daily. I notice every doctor has their own plan. I believe in a way it’s kind of like hit or miss because there really is no magic magic plan each of us just hopes we start feeling better!!! With this MTX I get the feeling it works very slowly before you start feeling better. I’m trying to be as patient as I can after trying so many different medication’s. My very best wishes to you!!!

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Hello @lindaadele I am now near the end of week 6 of MTX. 7th dose will be Sunday at supper.
My dizziness has definitely gotten worse, especially upon getting out of bed and most of the morning.
Had a telephone appt with Rheumatologist and she wants me to start tapering off prednisone (I am currently on 11 mg) 1 mg at a time every two weeks until 5 mg and then stay at that dosage until our next appointment end of July. I am also feeling kind of foggy in the head. A little spacey... for the most part I try to ignore all this and carry on as usual. If I get nervous I remind myself to just breathe ... it helps. How are you doing? Hope things are better for you.

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@michik

Hello @lindaadele I am now near the end of week 6 of MTX. 7th dose will be Sunday at supper.
My dizziness has definitely gotten worse, especially upon getting out of bed and most of the morning.
Had a telephone appt with Rheumatologist and she wants me to start tapering off prednisone (I am currently on 11 mg) 1 mg at a time every two weeks until 5 mg and then stay at that dosage until our next appointment end of July. I am also feeling kind of foggy in the head. A little spacey... for the most part I try to ignore all this and carry on as usual. If I get nervous I remind myself to just breathe ... it helps. How are you doing? Hope things are better for you.

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Great hearing from you! this Wednesday I will be on my eighth week of MTX. I take 10 mg each week. On the day I take the MTX I do get quite dizzy and brain fog. After a couple of days I feel somewhat better. right now the two medicines that I’m taking are MTX and hydroxychloroquine only. I go to my rheumatologist a week from this Thursday. I still have joint pain. Unfortunately I don’t do well with any of these medication‘s and I’ve been on quite a few already For PMR. i’m hoping for the best and I like what you said about just breathing unfortunately I know all about Breathing but I always forget to breathe! wishing you the very very very best !!!

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@lindaadele

Great hearing from you! this Wednesday I will be on my eighth week of MTX. I take 10 mg each week. On the day I take the MTX I do get quite dizzy and brain fog. After a couple of days I feel somewhat better. right now the two medicines that I’m taking are MTX and hydroxychloroquine only. I go to my rheumatologist a week from this Thursday. I still have joint pain. Unfortunately I don’t do well with any of these medication‘s and I’ve been on quite a few already For PMR. i’m hoping for the best and I like what you said about just breathing unfortunately I know all about Breathing but I always forget to breathe! wishing you the very very very best !!!

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Hello @lindaadele I am so sorry to hear you still have pain. This is such a frustrating and sometimes disheartening condition! I find it very confusing yet interesting to read about all the different treatment plans that rheumatologist put their patients on. At times when I read about the drugs used and see that the rate of success when used for PMR is not great it makes me wonder. That said our bodies all react differently.
I do hope your rheumatologist will be able to help you on Thursday and that all this will be behind you very soon. Wishing you all the very best! 🤞🙏

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@michik

Hello @lindaadele I am so sorry to hear you still have pain. This is such a frustrating and sometimes disheartening condition! I find it very confusing yet interesting to read about all the different treatment plans that rheumatologist put their patients on. At times when I read about the drugs used and see that the rate of success when used for PMR is not great it makes me wonder. That said our bodies all react differently.
I do hope your rheumatologist will be able to help you on Thursday and that all this will be behind you very soon. Wishing you all the very best! 🤞🙏

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I’m not sure if you got my last reply because I still don’t know how to work this website. I always love to hear from you and I always learn a lot from your post!!! I am still taking one day at a time and hoping for the best read which helps me a lot! wishing you the very best going forward!!!

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