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First chemo tomorrow--tips, suggestions, cautions?

Pancreatic Cancer | Last Active: Apr 20 5:05pm | Replies (51)

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@llad24

Hello everyone:
I know nobody has posted anything in a few years but I found a lot of the information here helpful. I'm starting my FOLFOX chemo next week and I was thinking about doing the Cryotherapy to prevent any neuropathy side effects. My oncologist gave me a big NO today when I asked for his opinion. I just don't understand why if there are people with good outcomes from it, why at least they don't support you if you want to try it.
I understand where he is coming from saying the Oxaliplatin changes the sensation of cold to pain but the point of Cryotherapy is to prevent the drug from doing that on the extremities. I'm so confused and frustrated right now. Not sure if I should still do it because at the end I will be the one dealing with the side effects but I don't want to go against my Oncologist's directions either. guess I will have the whole weekend to think about it. Are you guys still having neuropathy side effects years after your chemo treatment?

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Replies to "Hello everyone: I know nobody has posted anything in a few years but I found a..."

I don't know your specific situation so our experience may not be directly comparable. My wife had Folfirinox chemo for 12 cycles at the Fred Hutch cancer center in 2024. It was the standard practice of care for us to ice the feet and fingers every time during the Oxaliplatin infusion - in addition, my wife was very disciplined in taking ice chips orally to reduce possibility of neuropathy in the throat (she has esophageal dismotility). The latter made her nauseous but she persevered for 2 hours each time as the alternative was too risky from her perspective. She wore compression gloves on her hands/fingers while she held on to an classic ice pack filled with ice chips from home - the ice pack did the best job of conforming to her hands/fingers during the actual Oxaliplatin infusion. She still developed some neuropathy but now, at about 5 months later, the neuropathy in her fingers and feet is improving. Best wishes for you. I agree with another commenter that I would ask for the reason and study references that support it for you not to consider extremity icing as an option. Everyone is a unique case but I would want to understand the rationale and the data supporting it. The Hutch staff was very responsive when we wanted to understand an issue during treatment.

We had not heard of the icing when my husband was doing the folfox chemo, and his neuropathy is now severe. We started doing it when he changed to abrax/gem... but that was after a year of folfox and I think the damage was already done. I am not a doctor, but wish in hindsight that we had known of the icing and would have pursued that I think. But, everyone is different and I guess doctors feel differently about it helping or hurting.