Hi tk design. Wow that’s such a coincidence that you mentioned both the SI joint pain and dr Newson. Her clinic is in fact the one I am dealing with. I am one of their clients. She has many doctors working with her . They are following me up with blood tests and video call in three months from my start. Also I agree about the muscle and tissue loss. It’s so hard for me to exercise like I used to now, without aggravating my SI joints and being in pain for days or weeks. I manage to get a walk in every day if I have slept ok. Plus I have an exercise mat etc in my home. I can’t really wait for too long before I begin the estriadol though as my OP is quite severe in my spine and I don’t want to fracture. I am quite small framed so only weigh 48 Kg and at 168 cms tall that’s a low weight. Keep in touch