I used a cold cap too in 1999. Can’t say that I had safety issues. But I additionally had acupuncture right after each chemo and also went to a alopecia specialist who treated my hair weekly with potions of which I had no clue what they were. But I had actually been referred to him by my oncologist. All in all I didn’t loose my hair, it was just thinner and more brittle. I have a hair phobia, used to faint at hairdressers even as a child. So I put a lot of effort into keeping some kind of hair on my head! Good luck to you and may you be totally cleared of cancer.