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‘Big Guns’ - Triple Therapy with Double Chemo - How to prepare?
Prostate Cancer | Last Active: Apr 16 11:29am | Replies (13)Comment receiving replies
Lung nodules can be a little tricky to treat, but they can Use SBRT to eliminate them. It is recommended that you start with ADT and abiraterone. For ADT you should request Orgovyx instead of Eligard, The daily pill is easier to manage and you don’t need to start off with Casodex To prevent a PSA flare. In some cases ADT and a secondary drug can reduce the lung metastasis so they are no longer visible. All depends on how they want to treat them.
It is recommended that people start with abiraterone and move on to a lutamide later. Here is an article that discusses this sequencing.
https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30688-6/abstract
If he has heart issues, then it may make more sense to go with Nubeqa. Abiraterone is tough on the heart and raises blood pressure for most.
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Thanks, @jeffmarc. I have been a fan of SRBT from reading papers, but our team isn’t a fan of SBRT above the diaphragm unless it a solitary nodule… we had hope for some directed therapy and even wondered about Lutetium, but I guess the game is to save some tools in the toolbox for later. And we asked about Orgovyx and the response was ‘ we haven't used it in triple therapy before’ - it wasn’t a no, but it wasn’t a yes. We will finalize with our oncologist next week. Thanks for responding - it’s scary to be starting with so many things when he hasn’t even done ADT or radiation of any kind.