Does anyone feel like giving up ?

Sometimes.
But you don't have the best medication for you. Side effects are depressing. Alendronate is causing stomach issues. Your doctors need to prescribe something different.
You might ask for a low dose of slowly infused Reclast. You get better bone benefit and bypass the stomach.
It is the best medication to follow Prolia.
I don't like the idea of these medications, but at your age I started Forteo. I was prepared for the worst but two years later I'm begging for extension and getting extended use.
If you quit with a Tscore of -4, especially after Prolia you are likely to fracture. A fracture will change your entire life in ways you can't imagine.
Quit the alendronate, but please don't quit. Demand better care.

I wish I could make up my mind. I keep on changing my decisions. I sometimes think I read too much about experiences of others that are negative but I want to know the good & bad. I guess that’s why we are all on here.

It is hard. Feeling like giving up is a sad and bad feeling. I am sorry you have the thought of giving up. I have had many illnesses in my life and sometimes I just take one step forward, one step forward...and fortunately have always gotten through eventually. Chronic Lyme disease and other tick illnesses (30 years misdiagnosed and Drs told me I was crazy), broken hip, cancer three times.

Osteoporosis is scary and I have had the feeling of giving up, but I am not going to yet because I am too scared to give up. I feel fortunate I live in a time when we can do something about osteoporosis, and fortunately I haven't had very bad reactions to the meds. I know some people have, and it is just awful.
There is a lot out there that can help, not much without potential side effects. Not everyone gets them. There are more medications coming down the pipeline.
I sat and researched, meanwhile getting enough calcium, D and K3 and exercise as much as you are able.

There is a man on here who did a super YouTube video explaining the drugs and what order to take them in. I depend on that as a blueprint. He has a vested interest.

Exercise and good nutrition is the basis for good health. It helps reduce inflammation. That is my focus now. I guess to get through what ails me, I research, and try to figure out my plan to move one step forward, even if it is small, like heel drops, just anything to make me feel like I have some control. After I research, I take the attitude, no guts, no glory, and take the plunge. Osteoporosis is hereditary for me and if I don't take the plunge, I will end up like people before me.

I also started yoga and that made me not so achy, by stretching. I lift weights, but I was very tight. I just started with daily yoga stretches. It helped me sleep better at night because pain didn't wake me up. And doing it daily, I see progress. If I don't do yoga, I wake up in the middle of the night achy, so I keep it up.

I hope you can get in a better place. Please remember not everyone gets bad reactions. I just had a bad reaction to Fosomax and it was temporary. Evenity and Reclast were ok.

I’ve told my story here before and I will keep telling it.
I had a Reclast infusion 12/12/24
It is now April and I am still having dizziness and heart rate issues. I had an awful response to this drug and was in the ER 3 times in one week. Started with the flu like symptoms which they say are normal to passing out within 48 hrs of getting it
I had acute colitis, severe esophagitis. I lost 10 pounds in two weeks and was out of work for almost 2 months.
I have tons of medical bills and issues I have never had before. Thank God I was able to get through most of this. I’m still working on the dizziness and heart rate issues. Although these types of terrible reactions are rare. They do happen. I am having a brain MRI on Tuesday just to make sure the dizziness is not from any other source.
I was a health 64 yr old woman and was frightened into picking a drug for my bone density. By all accounts Reclast is the lesser of all the poison. Well it is not !
When I scheduled my MRI scheduler told me it is not the first time she heard this story. So what does that tell you!
The best advice I can give is if you must choose something, go for a daily med. at least this way you have a bad side effect, you can stop it and will dissipate out of your body. I am stuck with this in my body for a good year anyway. Never again. Diet and exercise will be the key. I would rather take my chances.

annar, I appreciate your post very much. I can't click the like button about what has happened to you.

I am 67 and doing Forteo for the second time. First time was in 2016 with the full 24 months treatment, then Roloxafine. Please don't give up. I believe Forteo could help you. I was have severe back spasms which is a warning for me that I would fracture again, and Forteo stopped that in the first 3 months. In 2016 I had 13 compression fractures and have not fractured since. Maybe something to talk about with your doctor?

Thank you for taking the time to tell about your experience. I wish I could just decide. I think I am most upset about the idea of an infusion. I list my patents to cancer and I think the infusion part has left me with bad feelings.

I am sorry that you had such a negative reaction. I’m so afraid mysrlf because I don’t tolerate any meds . MY experience with Prolia was not good either . You advice is the best I’ve heard. Be well and hopefully strong. Thank you.

That was recommended to me Twice. I think the Dr said he was hesitant because of possible heart issues. I am becoming g so confused.

I do get weary. I just look toward the next day and promise myself that I will add a few more steps to my exercise routine. Also, I try to think of something I can do for someone, like calling a friend or relative who might like to hear from me. These small things help me with my mental woes for the day. I try to take my condition in small chunks. The whole of it all is way too much. I was inspired by hearing someone say, "it's hard by the yard, but a cinch by the inch.