I have had MG for about 6 years now. Had a lot of leg cramps early on. Could stop them by standing up as soon as they started. Happened many times daily. 6 years in they are very infrequent. I do take pyridostigmine 4 times daily. I have been on many treatments including Rituximab, IVIG, Solaris, Plasma Exchange, Steroids, Pulse Dose Steroids and now efgartigamod. Physical Therapy, Cardiopulmonary Rehab. 9 hospitalizations, 5 in ICU. I have not been in the hospital for over 2 years now. Work 4-6 hours in my Restoration Shop most days. Never give up.