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Lifting weights while on ADT: hitting a wall?

Prostate Cancer | Last Active: 1 day ago | Replies (59)

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@jporter

I was not sure whether to start a new post or add to this one. I had a biopsy about a month ago, then a petscan.

The cancer has spread to my lymph nodes. I am about to start a regimen with prednisone and zytiga plus injections of Leuprolide (aka Lupron), which is every 6 months.

After having a "minor stroke" two years ago I worked for awhile then retired. Last June I started lifting weights and have a trainer. I am 71.

Is it save to continue lifting weights?

I have only been following this support group for three days, so I am still coming up to speed on things.

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Replies to "I was not sure whether to start a new post or add to this one. I..."

Welcome to the unhappy club. I lift weights all thru the ADT treatments. Been on Zytiga- prednisone awhile ago. Had pelvic lymph nodes affected too. 28 RT trips took care of that. Psa is < .01 for 27 months now. Soon to stop ADT altogether. Age now is 76.

Hi @jporter
Additional background would be helpful for others to formulate better replies to your question such as when were you diagnosed, what was your PSA, what are your Gleason scores, have you had an MRI, Decipher Test or any other genetic testing done? When was the " minor stroke" and was it classified as a TIA or one of the other four categories of stroke?

If I were in your position, I would want the cardiologist, neruologist and my primary care doctors to confer with my medical oncologist on the best choice of ADT for me as well as the parameters of a safe resistance training and aerobic regimen given the history of stroke. As a patient, I would want to be reassured that the safety profiles of the ADT meds prescribed would be the best for me given a history of stroke, why they were chosen and what other medication options were considered . Both lupron and abiraterone have warnings about elevated risks of cardiovasclar events. Below are links to two studies to give you some background, If you don't want to wade through the entire study, skim down to the paragraph on SAFETY in the first link and RESULTS in the second link.

Way more than you asked for, but having had to deal with cancer treatment for my wife who suffered a stroke as a result of the chemo, these are my thoughts. Best wishes to you on a successful treatment and robust fitness program! I hope you will keep us updated on your journey so we may all learn from your experiences!
Bill
https://www.nejm.org/doi/full/10.1056/NEJMoa2004325#:~:text=After%2048%20weeks%20of%20treatment,is%20shown%20in%20Figure%202.&text=Cumulative%20Incidence%20of%20Major%20Adverse,on%20a%20Cox%20regression%20model.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8437777/#:~:text=32%2C%2033%2C%2034%20In%20an,risk%20for%20stroke%20or%20MI.

Jporter. Was it a PSMA-PET?

Not a Doctor but surprised if cancer has spread to lymph nodes, was surgery and or radiation on the table or did your past history effect the path ?