FYI my pain doc said it's fine to take with "rescue meds" NSAIDS Acetaminophine which I do take or even Tramadol which I choose not to take. I'm a nerd so i tried to send you the research trajectory which was very interesting but this platform blocks AI generated material..You can find it by using Chat or deepseek and asking this "detail the 50-year research arc behind this drug, synthesizing hard data from patents, NIH archives, and biotech development timelines" I am a big nerd so probably boring to most.