At the recommendation of my urologist, I used a large pearl-sized dollop every other day until the symptoms started to subside. Then, I continued for a few weeks at twice a week. I was amazed at the success as I had been suffering for several months. Now, I use it only as needed if I feel symptoms starting to come on, and that’s usually only for a week. It was a miracle for me as I haven't had symptoms in almost a year.