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P1NP number on Tymlos

Osteoporosis & Bone Health | Last Active: Apr 14 1:02pm | Replies (19)
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@gently

zooie, most concerning is the serum calcium. Maybe ask the PA for ionic calcium levels. That gives you the metabolically active calcium level. Both the elevated levels ALP and the calcium reflect the high bone turnover rate. If you can get a lab order for PTH at the same time, you'll get another clue about what is going on. You might try skipping the injection the night before the serum testing. For most people Tymlos leaves the system within four hours. You might be processing it more slowly, which could affect the labs.
Are you having any side effects from high calcium.

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Replies to "zooie, most concerning is the serum calcium. Maybe ask the PA for ionic calcium levels. That..."
zooie | @zooie | Apr 5 9:32pm

Thank you! Yes, I will ask the PA for both the ionic calcium and PTH tests. And good idea, I will skip the injection the night before the blood draw.
As for side effects, I have brain fog, poor sleep, poor appetite, weight loss, leg cramps, decreased muscle strength, but I had attributed all that to losing my spouse a few months ago.
So I'm unsure if some of that might be partially due to the high calcium.

Yes, I am planning on getting both a dexa and a rems. I have alot of osteoarthritis and I have not been able to get a spine reading on the dexa and I also have had hip replacement.

As for why the bone loss? I'm only 100lbs and also have had I-131 treatment for graves disease and am on thyroid meds. I suspect my calcium and protein intake were on the low side.

Any other suggestions? I will report back after my PA visit and the additional tests.

Thank you!

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