Prolia every 6 months, I have not tried anything else except diet and exercise, but I live in the northwest so vit D3 deficient,and I am 54 but postmenopausal by 15 years and took tamoxifen, and now Arimidex. A few years back I took a leap of faith off of a bucking horse and broke quite a few bones. The doc ordered a dexascan and I started prolia and vitaminD3, and calcium, and a walking regimen. I will find out in 6 months how well I am doing.