evysar26- If I were you, I would ask your doctor why she/he selected Prolia. I know that it is a monoclonal antibody, and think it is often prescribed for patients who cannot sit up for 30 minutes or do not tolerate bisphonsphonates. Prolia may be more effective for osteoporosis caused by certain body conditions. Certain drugs have been more effective for the spine, certain for other areas. Prolia I think is given twice a year, whereas Tymlos and Forteo require daily injections. Certain conditions that I do not have would preclude use of Tymlos/Forteo. For me, the opportunity to build not just save bone is made these the PTH analog durgs worth the risks. Seems like most osteo drugs have a long list of side effects. For me, the possible risks of the effects of osteoporosis were worse than the listed possible side effects of Tymlos. In particular, I understand that if ones spine is weakened by osteoporosis, one can get painful compression fractures just by coughing. Friends whose moms (decades older than I am) have osteoporosis in the spine told me that their moms were in great pain. What risks to bear is a personal decision. Luckily, with Tymlos, I have not had the leg pain or other bad side effects mentioned here. I understand that vitamins and exercise have worked for some people; they have not for me staved off bone loss.